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Rat RCN3 Protein, His Tag

Rat RCN3 Protein, His Tag

产品编号

KMP4256

别名

网状局部蛋白3, RCN3 Protein, Rat RCN3 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias网状局部蛋白3, RCN3 Protein, Rat RCN3 Protein, His Tag
Catalog NumberKMP4256
Product DescriptionThe Rat RCN3 Protein(KMP4256) is produced in HEK293 Cells. A DNA sequence encoding the rat Rcn3 (Met1-His324) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameRCN3
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundRCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight36.4 kDa

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