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Rat P-Selectin Protein, hFc Tag

Rat P-Selectin Protein, hFc Tag

产品编号

KMP4237

别名

P-选择素, P-Selectin Protein, Rat P-Selectin Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasP-选择素, P-Selectin Protein, Rat P-Selectin Protein, hFc Tag
Catalog NumberKMP4237
Product DescriptionThe Rat P-Selectin Protein(KMP4237) is produced in HEK293 Cells. A DNA sequence encoding the rat Selp (AAI01920.1) (Met1-Gln700) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameP-Selectin
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundP selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P selectin is a cell adhesion molecule on the surface of activated endothelial cells. Cellular adhesion molecules are a large family of proteins that attach the cytoskeleton and intracellular signaling cascades with the extracellular environment. SELP is a calcium-dependent receptor for myeloid cells that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight98.7 kDa

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