Rat IL-20 Protein_天津卡梅德科技发展有限公司

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Rat IL-20 Protein

Rat IL-20 Protein

产品编号

KMP4229

别名

白细胞介素20, IL-20 Protein, Rat IL-20 Protein

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素20, IL-20 Protein, Rat IL-20 Protein
Catalog Number	KMP4229
Product Description	The Rat IL-20 Protein(KMP4229) is produced in E. coli. A DNA sequence encoding the rat IL20 (P11762) (Leu25-Leu176) is expressed and purified.
Molecular Name	IL-20
Species	Rat
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, 20% Glycerol, pH7.4
Background	IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. It has been shown that interleukin-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	17.7 kDa

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