Rat CD150 Protein, hFc Tag
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产品编号
KMP4223
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别名
信号淋巴细胞激活分子家族成员1, CD150 Protein, Rat CD150 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 信号淋巴细胞激活分子家族成员1, CD150 Protein, Rat CD150 Protein, hFc Tag |
Catalog Number | KMP4223 |
Product Description | The Rat CD150 Protein(KMP4223) is produced in HEK293 Cells. A DNA sequence encoding the rat Slamf1 (NP_001102548.1) (Met1-Leu242) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | CD150 |
Species | Rat |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 51.3 kDa |