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Rat CD150 Protein, hFc Tag

Rat CD150 Protein, hFc Tag

产品编号

KMP4223

别名

信号淋巴细胞激活分子家族成员1, CD150 Protein, Rat CD150 Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias信号淋巴细胞激活分子家族成员1, CD150 Protein, Rat CD150 Protein, hFc Tag
Catalog NumberKMP4223
Product DescriptionThe Rat CD150 Protein(KMP4223) is produced in HEK293 Cells. A DNA sequence encoding the rat Slamf1 (NP_001102548.1) (Met1-Leu242) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameCD150
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight51.3 kDa

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