Rat DSC2 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Rat DSC2 Protein, hFc Tag

Rat DSC2 Protein, hFc Tag

产品编号

KMP4214

别名

桥粒糖蛋白2, DSC2 Protein, Rat DSC2 Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	桥粒糖蛋白2, DSC2 Protein, Rat DSC2 Protein, hFc Tag
Catalog Number	KMP4214
Product Description	The Rat DSC2 Protein(KMP4214) is produced in HEK293 Cells. A DNA sequence encoding the rat DSC2 (Q3T1K6) (Met1-Pro694) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	DSC2
Species	Rat
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal aa followed by an in-frame stop codon. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in DSC2 are associated with arrhythmogenic right ventricular dysplasia-11. DSC2 is Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSC2 may contribute to epidermal cell positioning by mediating differential adhesiveness between cells that express different isoforms.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	101.6 kDa

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