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Rat CD27 Protein, mFc Tag

Rat CD27 Protein, mFc Tag

产品编号

KMP4212

别名

肿瘤坏死因子受体超家族成员7, CD27 Protein, Rat CD27 Protein, mFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子受体超家族成员7, CD27 Protein, Rat CD27 Protein, mFc Tag
Catalog NumberKMP4212
Product DescriptionThe Rat CD27 Protein(KMP4212) is produced in HEK293 Cells. A DNA sequence encoding the rat CD27 (NP_001019506.1) (Met1-Cys181) is expressed with the Fc region of Mouse IgG2a at the C-terminus.
Molecular NameCD27
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight44.1 kDa

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