Rat CD27 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Rat CD27 Protein, hFc Tag

Rat CD27 Protein, hFc Tag

产品编号

KMP4211

别名

肿瘤坏死因子受体超家族成员7, CD27 Protein, Rat CD27 Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体超家族成员7, CD27 Protein, Rat CD27 Protein, hFc Tag
Catalog Number	KMP4211
Product Description	The Rat CD27 Protein(KMP4211) is produced in HEK293 Cells. A DNA sequence encoding the rat CD27 (NP_001019506.1) (Met1-Arg183) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	CD27
Species	Rat
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	45 kDa

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