Rat IL21 Protein_天津卡梅德科技发展有限公司

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Rat IL21 Protein

Rat IL21 Protein

产品编号

KMP4209

别名

白细胞介素21, IL21 Protein, Rat IL21 Protein

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素21, IL21 Protein, Rat IL21 Protein
Catalog Number	KMP4209
Product Description	The Rat IL21 Protein(KMP4209) is produced in E. coli. A DNA sequence encoding the rat IL21 (NP_001102413.1) (Pro25-Ser146) is expressed with an initial Met.
Molecular Name	IL21
Species	Rat
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	14.5 kDa

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