Rat TNFSF12 Protein, hFc Tag
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产品编号
KMP4205
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别名
TNF超家族成员12, TNFSF12 Protein, Rat TNFSF12 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | TNF超家族成员12, TNFSF12 Protein, Rat TNFSF12 Protein, hFc Tag |
Catalog Number | KMP4205 |
Product Description | The Rat TNFSF12 Protein(KMP4205) is produced in HEK293 Cells. A DNA sequence encoding the rat TNFSF12 (NP_001001513.2)(Arg105-His249) is expressed with Fc region of human IgG1 at the N-terminus. |
Molecular Name | TNFSF12 |
Species | Rat |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 44.4 kDa |