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Rat TFRC Protein, His Tag

Rat TFRC Protein, His Tag

产品编号

KMP4199

别名

转铁蛋白受体1, TFRC Protein, Rat TFRC Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias转铁蛋白受体1, TFRC Protein, Rat TFRC Protein, His Tag
Catalog NumberKMP4199
Product DescriptionThe Rat TFRC Protein(KMP4199) is produced in HEK293 Cells. A DNA sequence encoding the Rat TFRC (Q99376) (Gly87-Phe761) is expressed, with a polyhistidine tag at the N-terminus.
Molecular NameTFRC
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 150mM NaCl, 0.02% Tween80, 5% Mannitol, pH7.5
BackgroundTransferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC/CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC/CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC/CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight78.59 kDa

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