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Rat CXCL10 Protein, His Tag

Rat CXCL10 Protein, His Tag

产品编号

KMP4192

别名

CXC趋化因子配体10, CXCL10 Protein, Rat CXCL10 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasCXC趋化因子配体10, CXCL10 Protein, Rat CXCL10 Protein, His Tag
Catalog NumberKMP4192
Product DescriptionThe Rat CXCL10 Protein(KMP4192) is produced in Yeast. A DNA sequence encoding the rat CXCL10 (NP_620789.1) (Ile22-Pro98) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameCXCL10
SpeciesRat
HostYeast
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
Background(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight10 kDa

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