Mouse IL15 & IL15RA Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse IL15 & IL15RA Protein, His Tag

Mouse IL15 & IL15RA Protein, His Tag

产品编号

KMP4162

别名

IL15和IL15RA的异二聚体蛋白, IL15 & IL15RA Protein, Mouse IL15 & IL15RA Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	IL15和IL15RA的异二聚体蛋白, IL15 & IL15RA Protein, Mouse IL15 & IL15RA Protein, His Tag
Catalog Number	KMP4162
Product Description	The Mouse IL15 & IL15RA Protein(KMP4162) is produced in HEK293 Cells. A DNA sequence encoding the Mouse IL15 (P48346-1)(Met1-Ser162) is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the Mouse IL15RA (Q60819-1) (Met1-Lys205) is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the IL15 & IL15RA heterodimer is purified.
Molecular Name	IL15 & IL15RA
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	IL-15 and IL-15 receptor alpha (IL-15Rα) play a significant role in multiple aspects of T cell biology. Interleukin (IL)-15 is essential for natural killer (NK), NKT and memory (m) CD8+ T cell development and function, and is currently under investigation as an immunotherapeutic agent for the treatment of cancer. Recently, the creation of IL-15 superagonist by complexing IL-15 and its high affinity receptor alpha (IL-15 Rα) in solution, inspired by the natural trans-presentation of IL-15, advances the potential of IL-15-based tumor immunotherapy. Gene therapy using engineered cells co-expressing IL-15/IL-15 Rα complex for cancer treatment is also emerging.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34.46 kDa

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