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Mouse GPRC5D Protein, Flag Tag

Mouse GPRC5D Protein, Flag Tag

产品编号

KMP4142

别名

G蛋白偶联受体家族C组5成员D, GPRC5D Protein, Mouse GPRC5D Protein, Flag Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasG蛋白偶联受体家族C组5成员D, GPRC5D Protein, Mouse GPRC5D Protein, Flag Tag
Catalog NumberKMP4142
Product DescriptionThe Mouse GPRC5D Protein(KMP4142) is produced in HEK293 Cells. A DNA sequence encoding the Mouse GPRC5D (Q9JIL6-2) (Met1-Cys300) is expressed.
Molecular NameGPRC5D
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Hepes, 150mM NaCl, 10% Trehalose, pH7.2
BackgroundOrphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight35.8 kDa

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