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Mouse PSCA Protein, His Tag

Mouse PSCA Protein, His Tag

产品编号

KMP4135

别名

前列腺干细胞抗原, PSCA Protein, Mouse PSCA Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias前列腺干细胞抗原, PSCA Protein, Mouse PSCA Protein, His Tag
Catalog NumberKMP4135
Product DescriptionThe Mouse PSCA Protein(KMP4135) is produced in HEK293 Cells. A DNA sequence encoding the Mouse PSCA (P57096) (Met1-Asn95) is expressed with a polyhistidine tag at the C-terminus.
Molecular NamePSCA
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundProstate Stem Cell Antigen (PSCA) is frequently expressed in prostate cancer. Prostate stem cell antigen (PSCA) is a cell-membrane glycoprotein consisting of 123 amino acids. Knockdown of PSCA induced EMT and reduced metastatic potentials of the DU145 cells, suggesting that PSCA played an important role in prostatic carcinogenesis and progression. PSCA gene plays an important role in cell adhesion, proliferation and survival. Increasing studies have focused on the association of PSCA gene rs2294008 C>T and rs2976392 G>A with cancer risk.PSCA expression is detected in over 80% of patients with local disease, and elevated levels of PSCA are correlated with increased tumor stage, grade, and androgen independence, including high expression in bone metastases.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight9.83 kDa

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