Mouse PSCA Protein, His Tag
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产品编号
KMP4135
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别名
前列腺干细胞抗原, PSCA Protein, Mouse PSCA Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 前列腺干细胞抗原, PSCA Protein, Mouse PSCA Protein, His Tag |
Catalog Number | KMP4135 |
Product Description | The Mouse PSCA Protein(KMP4135) is produced in HEK293 Cells. A DNA sequence encoding the Mouse PSCA (P57096) (Met1-Asn95) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | PSCA |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Prostate Stem Cell Antigen (PSCA) is frequently expressed in prostate cancer. Prostate stem cell antigen (PSCA) is a cell-membrane glycoprotein consisting of 123 amino acids. Knockdown of PSCA induced EMT and reduced metastatic potentials of the DU145 cells, suggesting that PSCA played an important role in prostatic carcinogenesis and progression. PSCA gene plays an important role in cell adhesion, proliferation and survival. Increasing studies have focused on the association of PSCA gene rs2294008 C>T and rs2976392 G>A with cancer risk.PSCA expression is detected in over 80% of patients with local disease, and elevated levels of PSCA are correlated with increased tumor stage, grade, and androgen independence, including high expression in bone metastases. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 9.83 kDa |