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Mouse ALDH1A3 Protein, His Tag

Mouse ALDH1A3 Protein, His Tag

产品编号

KMP4120

别名

醛脱氢酶 1 家族成员 A3, ALDH1A3 Protein, Mouse ALDH1A3 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias醛脱氢酶 1 家族成员 A3, ALDH1A3 Protein, Mouse ALDH1A3 Protein, His Tag
Catalog NumberKMP4120
Product DescriptionThe Mouse ALDH1A3 Protein(KMP4120) is produced in E. coli. A DNA sequence encoding the Mouse ALDH1A3 (Q9JHW9) (Ala2-Pro512) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameALDH1A3
SpeciesMouse
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM TRIS, 50mM NaCl pH8.0
BackgroundAldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight56.94 kDa

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