Mouse ALDH1A3 Protein, His Tag
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产品编号
KMP4120
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别名
醛脱氢酶 1 家族成员 A3, ALDH1A3 Protein, Mouse ALDH1A3 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 醛脱氢酶 1 家族成员 A3, ALDH1A3 Protein, Mouse ALDH1A3 Protein, His Tag |
Catalog Number | KMP4120 |
Product Description | The Mouse ALDH1A3 Protein(KMP4120) is produced in E. coli. A DNA sequence encoding the Mouse ALDH1A3 (Q9JHW9) (Ala2-Pro512) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | ALDH1A3 |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 50mM TRIS, 50mM NaCl pH8.0 |
Background | Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 56.94 kDa |