Mouse CD30 Protein, His Tag
-
产品编号
KMP4117
-
别名
白细胞抗原分化簇30, CD30 Protein, Mouse CD30 Protein, His Tag
-
规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞抗原分化簇30, CD30 Protein, Mouse CD30 Protein, His Tag |
Catalog Number | KMP4117 |
Product Description | The Mouse CD30 Protein(KMP4117) is produced in HEK293 Cells. A DNA sequence encoding the Mouse TNFRSF8 ( NP_033427.1) (Met1-Thr258) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | CD30 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD). |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 26.6 kDa |