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Mouse NKG2D Protein, hFc Tag

Mouse NKG2D Protein, hFc Tag

产品编号

KMP4107

别名

杀伤细胞类凝集素受体K亚家族成员1, NKG2D Protein, Mouse NKG2D Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias杀伤细胞类凝集素受体K亚家族成员1, NKG2D Protein, Mouse NKG2D Protein, hFc Tag
Catalog NumberKMP4107
Product DescriptionThe Mouse NKG2D Protein(KMP4107) is produced in Insect Cells. A DNA sequence encoding the Mouse KLRK1 (NP_001076791.1) (Phe77-Val219) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular NameNKG2D
SpeciesMouse
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 250mM NaCl, 10% Glycerol, pH8.0
BackgroundKLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight44.9 kDa

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