Mouse Allergin 1 Protein, hFc Tag
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产品编号
KMP4095
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别名
肥大细胞免疫球蛋白样受体1, Allergin 1 Protein, Mouse Allergin 1 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 肥大细胞免疫球蛋白样受体1, Allergin 1 Protein, Mouse Allergin 1 Protein, hFc Tag |
Catalog Number | KMP4095 |
Product Description | The Mouse Allergin 1 Protein(KMP4095) is produced in HEK293 Cells. A DNA sequence encoding the Mouse MILR1 (NP_001028607.1) (Met1-Ser150) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | Allergin 1 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to suppress immunoglobulin E (IgE)-mediated, mast cell-dependent responses in both mice and humans. The C allele of rs6504230 was associated with increased expression of MILR1, which was following the results of expression quantitative trait loci analysis using human leukocytes. The rs6504230 polymorphism affects MILR1 expression levels in humans, leading to a susceptibility to producing specific IgE antibodies against common allergens. Diseases associated with MILR1 include Mitochondrial Dna Depletion Syndrome 16 and Autosomal Dominant Progressive External Ophthalmoplegia. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 39.8 kDa |