Mouse RGMB Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse RGMB Protein, His Tag

Mouse RGMB Protein, His Tag

产品编号

KMP4089

别名

排斥性引导分子BMP辅助受体b, RGMB Protein, Mouse RGMB Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	排斥性引导分子BMP辅助受体b, RGMB Protein, Mouse RGMB Protein, His Tag
Catalog Number	KMP4089
Product Description	The Mouse RGMB Protein(KMP4089) is produced in HEK293 Cells. A DNA sequence encoding the Mouse RGMB (NP_848730.2) (Met1-Cys415) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	RGMB
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investigations demonstrated RGMB knockdown resulted in a reduced expression and activity of Caspase-3, accompanied with better survival in RGMB knockdown cells under serum starvation, which might be induced by its repression on MAPK JNK pathway. That RGMB may act as a negative regulator in breast cancer through BMP signaling.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	41.6 kDa

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