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Mouse LAG3 Protein

Mouse LAG3 Protein

产品编号

KMP4083

别名

淋巴细胞活化基因3, LAG3 Protein, Mouse LAG3 Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias淋巴细胞活化基因3, LAG3 Protein, Mouse LAG3 Protein
Catalog NumberKMP4083
Product DescriptionThe Mouse LAG3 Protein(KMP4083) is produced in HEK293 Cells. A DNA sequence encoding the Mouse LAG3 (NP_032505.1) (Met1-Leu442) is expressed.
Molecular NameLAG3
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundLAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight45.25 kDa

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