Mouse TMED1 Protein, hFc Tag
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产品编号
KMP4079
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别名
跨膜p24运输蛋白1, TMED1 Protein, Mouse TMED1 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 跨膜p24运输蛋白1, TMED1 Protein, Mouse TMED1 Protein, hFc Tag |
Catalog Number | KMP4079 |
Product Description | The Mouse TMED1 Protein(KMP4079) is produced in HEK293 Cells. A DNA sequence encoding the Mouse TMED1 (NP_034874.2) (Met1-Asn194) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | TMED1 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription from the IL8 promoter and most likely requires other proteins to elicit these activities. Dendritic cells from Peyer's patches (but not from spleen) express TMED1 in response to treatment with LPS. TMED1 may play a role in vesicular protein trafficking, mainly in the early secretory pathway. It may act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 46 kDa |