Mouse PIK3IP1 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse PIK3IP1 Protein, His Tag

Mouse PIK3IP1 Protein, His Tag

产品编号

KMP4075

别名

磷酸肌醇3激酶相互作用蛋白1, PIK3IP1 Protein, Mouse PIK3IP1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	磷酸肌醇3激酶相互作用蛋白1, PIK3IP1 Protein, Mouse PIK3IP1 Protein, His Tag
Catalog Number	KMP4075
Product Description	The Mouse PIK3IP1 Protein(KMP4075) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Pik3ip1 (NP_835362.2) (Met1-Leu170) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	PIK3IP1
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, metabolism and survival in most cell types. Proper liver function and development highly depend on intact PI3K signal transduction. Aberrant PI3K pathway signaling in the liver is associated with hepatocellular carcinoma. PI3K signaling is involved in the homeostasis of lipid and glucose metabolism. Activation of the PI3K pathway induces lipogenesis and glycogenesis in the liver, since both Akt overexpressing transgenic mice and PTEN knockout mice develop fatty liver and hypoglycemia. PIK3IP1 overexpression can contribute to glucose homeostasis and fatty deposition.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	17.5 kDa

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