Mouse Peroxiredoxin 2 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse Peroxiredoxin 2 Protein, His Tag

Mouse Peroxiredoxin 2 Protein, His Tag

产品编号

KMP4069

别名

过氧化物酶2, Peroxiredoxin 2 Protein, Mouse Peroxiredoxin 2 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	过氧化物酶2, Peroxiredoxin 2 Protein, Mouse Peroxiredoxin 2 Protein, His Tag
Catalog Number	KMP4069
Product Description	The Mouse Peroxiredoxin 2 Protein(KMP4069) is produced in Insect Cells. A DNA sequence encoding the Mouse PRDX2 (NP_035693.3) (Met1-Asn198) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	Peroxiredoxin 2
Species	Mouse
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM Tris,150mM NaCl,10% Glycerol,0.5mM TCEP, pH7.5
Background	Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein that belongs to the ahpC/TSA family. Peroxiredoxin-2/PRDX2 contains one thioredoxin domain. Peroxiredoxin-2/PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2/PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2/PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins/Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins/Prx family is divided into six groups (PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins/Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins/Prx has a proliferative effect and may be related to cancer development or progression.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	24.1 kDa

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