Mouse VISTA Protein, hFc Tag_天津卡梅德科技发展有限公司

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Mouse VISTA Protein, hFc Tag

Mouse VISTA Protein, hFc Tag

产品编号

KMP4066

别名

含V型免疫球蛋白结构域的T细胞活化抑制因子, VISTA Protein, Mouse VISTA Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	含V型免疫球蛋白结构域的T细胞活化抑制因子, VISTA Protein, Mouse VISTA Protein, hFc Tag
Catalog Number	KMP4066
Product Description	The Mouse VISTA Protein(KMP4066) is produced in HEK293 Cells. A DNA sequence encoding the Mouse C10orf54 (NP_083008.1) (Met1-Ala191) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	VISTA
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	44.5 kDa

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