Mouse Rab2 Protein, His Tag
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产品编号
KMP4055
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别名
Ras相关蛋白Rab-2A, Rab2 Protein, Mouse Rab2 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | Ras相关蛋白Rab-2A, Rab2 Protein, Mouse Rab2 Protein, His Tag |
Catalog Number | KMP4055 |
Product Description | The Mouse Rab2 Protein(KMP4055) is produced in E. coli. A DNA sequence encoding the Mouse Rab2a (NP_067493.1) (Met1-Cys212) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | Rab2 |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 25.8 kDa |