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Mouse GAPDH Protein, His Tag

Mouse GAPDH Protein, His Tag

产品编号

KMP4050

别名

甘油醛-3-磷酸脱氢酶, GAPDH Protein, Mouse GAPDH Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias甘油醛-3-磷酸脱氢酶, GAPDH Protein, Mouse GAPDH Protein, His Tag
Catalog NumberKMP4050
Product DescriptionThe Mouse GAPDH Protein(KMP4050) is produced in E. coli. A DNA sequence encoding the Mouse GAPDH (P16858) (Met1-Glu333) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameGAPDH
SpeciesMouse
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 200mM Arg, 10% Glycerol
BackgroundGlyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight37.9 kDa

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