Mouse LDHA Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse LDHA Protein, His Tag

Mouse LDHA Protein, His Tag

产品编号

KMP4049

别名

乳酸脱氢酶A, LDHA Protein, Mouse LDHA Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	乳酸脱氢酶A, LDHA Protein, Mouse LDHA Protein, His Tag
Catalog Number	KMP4049
Product Description	The Mouse LDHA Protein(KMP4049) is produced in E. coli. A DNA sequence encoding the Mouse Ldha (NP_034829.1) (Met1-Phe332) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	LDHA
Species	Mouse
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, 10% Glycerol, pH7.4
Background	LDHA (Lactate Dehydrogenase A) is a Protein Coding gene. The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA, a key enzyme regulating aerobic glycolysis, belongs to the lactate dehydrogenase family and is overexpressed in many human cancers, and correlates with poor clinical outcomes. LDHA can promote the Warburg effect to produce lactate and Adenosine Triphosphate (ATP) in aerobic conditions, which contributes to oncogenesis metastasis and drug resistance in various cancers. Up-regulation of lactate dehydrogenase LDHA is a frequent event in human malignancies and relate to poor postoperative outcome. Diseases associated with LDHA include Fanconi-Bickel Syndrome and Myoglobinuria.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	36.5 kDa

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