Mouse TSC22D1 Protein, His Tag
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产品编号
KMP4048
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别名
TSC22域家族成员1, TSC22D1 Protein, Mouse TSC22D1 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | TSC22域家族成员1, TSC22D1 Protein, Mouse TSC22D1 Protein, His Tag |
Catalog Number | KMP4048 |
Product Description | The Mouse TSC22D1 Protein(KMP4048) is produced in E. coli. A DNA sequence encoding the Mouse Tsc22d1 (NP_033392.1) (Met1-Ala143) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | TSC22D1 |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor that negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 17.8 kDa |