Mouse MDC Protein, His Tag
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产品编号
KMP4022
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别名
刺激性T细胞趋化蛋白1, MDC Protein, Mouse MDC Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 刺激性T细胞趋化蛋白1, MDC Protein, Mouse MDC Protein, His Tag |
Catalog Number | KMP4022 |
Product Description | The Mouse MDC Protein(KMP4022) is produced in E. coli. A DNA sequence encoding the Mouse CCL22 (O88430) (Gly26-Ser92) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | MDC |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 0.1% TFA, 50% Acetonitrile |
Background | Chemokine (C-C motif) ligand 22(ABCD-1/CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1/CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated/effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1/CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 9.9 kDa |