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Mouse MDC Protein, His Tag

Mouse MDC Protein, His Tag

产品编号

KMP4022

别名

刺激性T细胞趋化蛋白1, MDC Protein, Mouse MDC Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias刺激性T细胞趋化蛋白1, MDC Protein, Mouse MDC Protein, His Tag
Catalog NumberKMP4022
Product DescriptionThe Mouse MDC Protein(KMP4022) is produced in E. coli. A DNA sequence encoding the Mouse CCL22 (O88430) (Gly26-Ser92) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameMDC
SpeciesMouse
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation0.1% TFA, 50% Acetonitrile
BackgroundChemokine (C-C motif) ligand 22(ABCD-1/CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1/CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated/effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1/CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight9.9 kDa

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