Mouse IGFBP2 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse IGFBP2 Protein, His Tag

Mouse IGFBP2 Protein, His Tag

产品编号

KMP4012

别名

胰岛素样生长因子结合蛋白2, IGFBP2 Protein, Mouse IGFBP2 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	胰岛素样生长因子结合蛋白2, IGFBP2 Protein, Mouse IGFBP2 Protein, His Tag
Catalog Number	KMP4012
Product Description	The Mouse IGFBP2 Protein(KMP4012) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Igfbp2 (NP_032368.2) (Met1-Gln305) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	IGFBP2
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>70% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	IGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) through high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified. The six IGFBPs are structurally related but encoded by distinct genes. IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP-2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to the potential involvement of IGFBP-2 in tumorigenesis. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. It inhibits IGF-mediated growth and developmental rates.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	31 kDa

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