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Mouse BTLA Protein, His Tag

Mouse BTLA Protein, His Tag

产品编号

KMP4001

别名

B和T淋巴细胞衰减因子, BTLA Protein, Mouse BTLA Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasB和T淋巴细胞衰减因子, BTLA Protein, Mouse BTLA Protein, His Tag
Catalog NumberKMP4001
Product DescriptionThe Mouse BTLA Protein(KMP4001) is produced in HEK293 Cells. A DNA sequence encoding the Mouse BTLA (AAI08964.1) (Met1-Gly176) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameBTLA
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundBTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight21.54 kDa

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