Mouse FLT1 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse FLT1 Protein, His Tag

Mouse FLT1 Protein, His Tag

产品编号

KMP3997

别名

血管内皮生长因子受体1, FLT1 Protein, Mouse FLT1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	血管内皮生长因子受体1, FLT1 Protein, Mouse FLT1 Protein, His Tag
Catalog Number	KMP3997
Product Description	The Mouse FLT1 Protein(KMP3997) is produced in HEK293 Cells. A DNA sequence encoding the Mouse FLT1 (NP_034358.2) (Met1-Glu759) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	FLT1
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1/FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1/FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1/FLT1 is not expressed in tumor cell lines. VEGFR-1/FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1/FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	84.2 kDa

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