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Mouse TNFSF13 Protein, hFc Tag

Mouse TNFSF13 Protein, hFc Tag

产品编号

KMP3986

别名

肿瘤坏死因子配体超家族成员13, TNFSF13 Protein, Mouse TNFSF13 Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子配体超家族成员13, TNFSF13 Protein, Mouse TNFSF13 Protein, hFc Tag
Catalog NumberKMP3986
Product DescriptionThe Mouse TNFSF13 Protein(KMP3986) is produced in HEK293 Cells. A DNA sequence encoding the Mouse TNFSF13 (Q9D777) (Ala96-Leu240) is expressed with the fused Fc region of human IgG1 at the N-terminus.
Molecular NameTNFSF13
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA. TNFSF13 is lowly expressed in normal tissues, but is elevated in several types of tumors and transformed cell lines. It is important for B cell development. TNFSF13 may also play a role in T-independent type II antigen responses and T cell survival, and induce proliferation/survival of non lymphoid cells. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. TNFSF13 also has been demonstrated to bind to proteoglycans on the cell surface.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight44.8 kDa

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