Mouse Fractalkine Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse Fractalkine Protein, His Tag

Mouse Fractalkine Protein, His Tag

产品编号

KMP3979

别名

CX3C膜修饰趋化因子, Fractalkine Protein, Mouse Fractalkine Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	CX3C膜修饰趋化因子, Fractalkine Protein, Mouse Fractalkine Protein, His Tag
Catalog Number	KMP3979
Product Description	The Mouse Fractalkine Protein(KMP3979) is produced in Yeast. A DNA sequence encoding the Mouse Cx3cl1 (O35188) (Gln25-Lys105) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	Fractalkine
Species	Mouse
Host	Yeast
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine/CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine/CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	10.7 kDa

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