Mouse CD160 Protein, hFc Tag
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产品编号
KMP3970
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别名
自然杀伤细胞受体BY55, CD160 Protein, Mouse CD160 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 自然杀伤细胞受体BY55, CD160 Protein, Mouse CD160 Protein, hFc Tag |
Catalog Number | KMP3970 |
Product Description | The Mouse CD160 Protein(KMP3970) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Cd160 (NP_061237.3) (Met1-Leu159) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | CD160 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 41.9 kDa |