Mouse CD162 Protein_天津卡梅德科技发展有限公司

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Mouse CD162 Protein

Mouse CD162 Protein

产品编号

KMP3966

别名

P选择素糖蛋白配体1, CD162 Protein, Mouse CD162 Protein

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	P选择素糖蛋白配体1, CD162 Protein, Mouse CD162 Protein
Catalog Number	KMP3966
Product Description	The Mouse CD162 Protein(KMP3966) is produced in HEK293 Cells. A DNA sequence encoding the extracellular domain of Mouse SELPLG (Q62170) (Met1-Cys307) is expressed with six amino acids (LEVLFQ) at the C- terminus.
Molecular Name	CD162
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	31.2 kDa

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