Mouse CD93 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Mouse CD93 Protein, hFc Tag

Mouse CD93 Protein, hFc Tag

产品编号

KMP3964

别名

重组人补体C1q受体, CD93 Protein, Mouse CD93 Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组人补体C1q受体, CD93 Protein, Mouse CD93 Protein, hFc Tag
Catalog Number	KMP3964
Product Description	The Mouse CD93 Protein(KMP3964) is produced in HEK293 Cells. A DNA sequence encoding the Mouse CD93 (NP_034870.1) (Met1-Asn572) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	CD93
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	85.83 kDa

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