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Mouse HE4 Protein, His Tag

Mouse HE4 Protein, His Tag

产品编号

KMP3952

别名

人附睾蛋白4, HE4 Protein, Mouse HE4 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias人附睾蛋白4, HE4 Protein, Mouse HE4 Protein, His Tag
Catalog NumberKMP3952
Product DescriptionThe Mouse HE4 Protein(KMP3952) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Wfdc2 (NP_080599.1) (Met1-Phe174) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameHE4
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundWAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2/HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cAvities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2/HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight16.4 kDa

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