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Mouse NCR1 Protein, His Tag

Mouse NCR1 Protein, His Tag

产品编号

KMP3950

别名

天然细胞毒性触发受体1, NCR1 Protein, Mouse NCR1 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias天然细胞毒性触发受体1, NCR1 Protein, Mouse NCR1 Protein, His Tag
Catalog NumberKMP3950
Product DescriptionThe Mouse NCR1 Protein(KMP3950) is produced in HEK293 Cells. A DNA sequence encoding the Mouse NCR1 (NP_034876.2) (Met1-Asn255) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameNCR1
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNCR1, also known as NK-p46 and CD335, is a natural cytotoxicity receptor(NCR). NCRs are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells, pathogen-infected cell lines, and mononuclear phagocytes infected with an intracellular bacterium.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight28.6 kDa

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