Mouse NCR1 Protein, His Tag
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产品编号
KMP3950
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别名
天然细胞毒性触发受体1, NCR1 Protein, Mouse NCR1 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 天然细胞毒性触发受体1, NCR1 Protein, Mouse NCR1 Protein, His Tag |
Catalog Number | KMP3950 |
Product Description | The Mouse NCR1 Protein(KMP3950) is produced in HEK293 Cells. A DNA sequence encoding the Mouse NCR1 (NP_034876.2) (Met1-Asn255) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | NCR1 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | NCR1, also known as NK-p46 and CD335, is a natural cytotoxicity receptor(NCR). NCRs are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells, pathogen-infected cell lines, and mononuclear phagocytes infected with an intracellular bacterium. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 28.6 kDa |