Mouse SLAMF8 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse SLAMF8 Protein, His Tag

Mouse SLAMF8 Protein, His Tag

产品编号

KMP3942

别名

信号淋巴细胞激活分子家族成员8, SLAMF8 Protein, Mouse SLAMF8 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	信号淋巴细胞激活分子家族成员8, SLAMF8 Protein, Mouse SLAMF8 Protein, His Tag
Catalog Number	KMP3942
Product Description	The Mouse SLAMF8 Protein(KMP3942) is produced in HEK293 Cells. A DNA sequence encoding the Mouse SLAMF8 (NP_083360.2) extracellular domain (Met 1-Asp 231) is fused with the a polyhistidine tag at the C-terminus.
Molecular Name	SLAMF8
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>80% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, in association with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. Mouse SLAM family member 8, also known as B-lymphocyte activator macrophage expressed, BCM-like membrane protein, SLAMF8 and BLAME, is a single-pass type I membrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain. SLAMF8/BLAME is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	24.8 kDa

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