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Mouse CEL Protein, His Tag

Mouse CEL Protein, His Tag

产品编号

KMP3938

别名

羧基酯脂肪酶, CEL Protein, Mouse CEL Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias羧基酯脂肪酶, CEL Protein, Mouse CEL Protein, His Tag
Catalog NumberKMP3938
Product DescriptionThe Mouse CEL Protein(KMP3938) is produced in Insect Cells. A DNA sequence encoding the Mouse CEL (NP_034015.1) (Met1-Leu534) is expressed with a C-terminal polyhistidine tag.
Molecular NameCEL
SpeciesMouse
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 500mM NaCl, 10% Glycerol, pH7.4
BackgroundCEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL cause maturity-onset diabetes of the young as well as pancreatic exocrine dysfunction. The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight58.2 kDa

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