Mouse SPARCL1 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse SPARCL1 Protein, His Tag

Mouse SPARCL1 Protein, His Tag

产品编号

KMP3931

别名

富含半胱氨酸的酸性分泌蛋白类似蛋白1, SPARCL1 Protein, Mouse SPARCL1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	富含半胱氨酸的酸性分泌蛋白类似蛋白1, SPARCL1 Protein, Mouse SPARCL1 Protein, His Tag
Catalog Number	KMP3931
Product Description	The Mouse SPARCL1 Protein(KMP3931) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Sparcl1 (NP_034227.3) (Tyr368-Phe650) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	SPARCL1
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. Besides, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34.8 kDa

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