Mouse S100A4 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse S100A4 Protein, His Tag

Mouse S100A4 Protein, His Tag

产品编号

KMP3920

别名

S100钙结合蛋白A4, S100A4 Protein, Mouse S100A4 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	S100钙结合蛋白A4, S100A4 Protein, Mouse S100A4 Protein, His Tag
Catalog Number	KMP3920
Product Description	The Mouse S100A4 Protein(KMP3920) is produced in E. coli. A DNA sequence encoding the Mouse S100A4 (NP_035441.1) (Met1-Lys101) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	S100A4
Species	Mouse
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is necessary for S100A4 to interact with its protein targets and generate biological effects. It can bind the already known targets p53, F-actin, liprin β, myosin heavy chain II, and prevent their phosphorylation and multimerization. It has been demonstrated that S100A4 is directly involved in tumor metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation, and appears to be a metastasis factor and a molecular marker for clinical prognosis. Multiple alternatively spliced variants encoding the same protein have been identified.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	13.8 kDa

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