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Mouse S100A3 Protein, His Tag

Mouse S100A3 Protein, His Tag

产品编号

KMP3907

别名

S100钙结合蛋白 A3, S100A3 Protein, Mouse S100A3 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasS100钙结合蛋白 A3, S100A3 Protein, Mouse S100A3 Protein, His Tag
Catalog NumberKMP3907
Product DescriptionThe Mouse S100A3 Protein(KMP3907) is produced in E. coli. A DNA sequence encoding the Mouse S100A3 (NP_035440.1) (Met1-Gln101) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameS100A3
SpeciesMouse
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundProtein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3/S100E contains 2 EF-hand domains. S100A3/S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+ required for hair cuticular barrier formation. S100A3/S100E is a unique member of the Ca2+-binding S100 protein family with the highest cysteine content and affinity for Zn2+. S100A3/S100E binds both calcium and zinc. S100A3/S100E probably binds 2 zinc ions per molecule. It may be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. S100A3 plays an important role in calcium-dependent processes leading to hair shaft formation. S100A3/S100E is a unique protein among all members of the calcium-binding S100 family, is specifically expressed at the inner endocuticle of human hair fibers. Upon hair damage, S100A3/S100E is released from hair fibers and possibly destabilizes the hair tissue architecture.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight14 kDa

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