Mouse S100A3 Protein, His Tag
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产品编号
KMP3907
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别名
S100钙结合蛋白 A3, S100A3 Protein, Mouse S100A3 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | S100钙结合蛋白 A3, S100A3 Protein, Mouse S100A3 Protein, His Tag |
Catalog Number | KMP3907 |
Product Description | The Mouse S100A3 Protein(KMP3907) is produced in E. coli. A DNA sequence encoding the Mouse S100A3 (NP_035440.1) (Met1-Gln101) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | S100A3 |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Protein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3/S100E contains 2 EF-hand domains. S100A3/S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+ required for hair cuticular barrier formation. S100A3/S100E is a unique member of the Ca2+-binding S100 protein family with the highest cysteine content and affinity for Zn2+. S100A3/S100E binds both calcium and zinc. S100A3/S100E probably binds 2 zinc ions per molecule. It may be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. S100A3 plays an important role in calcium-dependent processes leading to hair shaft formation. S100A3/S100E is a unique protein among all members of the calcium-binding S100 family, is specifically expressed at the inner endocuticle of human hair fibers. Upon hair damage, S100A3/S100E is released from hair fibers and possibly destabilizes the hair tissue architecture. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 14 kDa |