Mouse CD8 alpha Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD8 alpha Protein, His Tag

Mouse CD8 alpha Protein, His Tag

产品编号

KMP3899

别名

T细胞表面糖蛋白CD8 Alpha 链, CD8 alpha Protein, Mouse CD8 alpha Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	T细胞表面糖蛋白CD8 Alpha 链, CD8 alpha Protein, Mouse CD8 alpha Protein, His Tag
Catalog Number	KMP3899
Product Description	The Mouse CD8 alpha Protein(KMP3899) is produced in HEK293 Cells. A DNA sequence encoding the CD8a (NP_001074579.1) (Met1-Tyr196) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular Name	CD8 alpha
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	20.3 kDa

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