Mouse CD16 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Mouse CD16 Protein, His Tag, Avi Tag

Mouse CD16 Protein, His Tag, Avi Tag

产品编号

KMP3889

别名

低亲和力免疫球蛋白γFc段受体III-A, CD16 Protein, Mouse CD16 Protein, His Tag, Avi Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	低亲和力免疫球蛋白γFc段受体III-A, CD16 Protein, Mouse CD16 Protein, His Tag, Avi Tag
Catalog Number	KMP3889
Product Description	The Mouse CD16 Protein(KMP3889) is produced in HEK293 Cells. A DNA sequence encoding the Mouse FCGR3 (P08508.1) (Met1-Thr215) is expressed with a c-terminal polyhistidine tagged Avi tag at the C-terminus. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CD16
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	24.4 kDa

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