Mouse AGRP Protein, hFc Tag
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产品编号
KMP3879
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别名
重组人刺鼠相关蛋白, AGRP Protein, Mouse AGRP Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 重组人刺鼠相关蛋白, AGRP Protein, Mouse AGRP Protein, hFc Tag |
Catalog Number | KMP3879 |
Product Description | The Mouse AGRP Protein(KMP3879) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Agrp (NP_031453.1) (Ser82-Thr131) is expressed with the Fc region of human IgG1 at the N-terminus. |
Molecular Name | AGRP |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >80% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 34.1 kDa |