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Mouse CD155 Protein, hFc Tag, Avi Tag

Mouse CD155 Protein, hFc Tag, Avi Tag

产品编号

KMP3877

别名

跨膜粘附蛋白, CD155 Protein, Mouse CD155 Protein, hFc Tag, Avi Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias跨膜粘附蛋白, CD155 Protein, Mouse CD155 Protein, hFc Tag, Avi Tag
Catalog NumberKMP3877
Product DescriptionThe Mouse CD155 Protein(KMP3877) is produced in HEK293 Cells. A DNA sequence encoding the Mouse PVR (NP_081790.1) (Met1-Arg345) is expressed with a C-terminal Fc region of human IgG1 tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular NameCD155
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight62.9 kDa

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