Mouse BDNF Protein, His Tag
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产品编号
KMP3872
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别名
脑源性神经营养因子, BDNF Protein, Mouse BDNF Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 脑源性神经营养因子, BDNF Protein, Mouse BDNF Protein, His Tag |
Catalog Number | KMP3872 |
Product Description | The Mouse BDNF Protein(KMP3872) is produced in HEK293 Cells. A DNA sequence encoding the Mouse BDNF (EDL27780.1, with mutation Arg 129 Ala, Arg 130 Ala) (Met1-Arg249) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | BDNF |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 27.4 kDa |