Mouse CXCL7 Protein, His Tag
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产品编号
KMP3857
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别名
前血小板碱性蛋白, CXCL7 Protein, Mouse CXCL7 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 前血小板碱性蛋白, CXCL7 Protein, Mouse CXCL7 Protein, His Tag |
Catalog Number | KMP3857 |
Product Description | The Mouse CXCL7 Protein(KMP3857) is produced in E. coli. A DNA sequence encoding the Mouse Ppbp (Q9EQI5) (Lys40-Tyr113) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | CXCL7 |
Species | Mouse |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >80% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 1/1000 TFA, 15% Acetonitrile |
Background | Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2/PPBP/CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2/PPBP/CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 10.4 kDa |